Malikul Chair1, zulkifli Amin, Noorwati, Andika Rachman,Pringgodigdo

1Departemen Ilmu Penyakit Dalam FKUI/RSCM2Divisi Respirologi dan Perawatan Penyakit Kritis, Departemen Ilmu Penyakit Dalam FKUI/RSCM3Divisi Hematologi dan Onkologi Medis, Departemen Ilmu Penyakit Dalam RS Kanker Dharmais4 Divisi Hematologi dan Onkologi Medis, Departemen Ilmu Penyakit Dalam FKUI/RSCM5Divisi Ginjal Hipertensi, Departemen Ilmu Penyakit Dalam FKUI/RSCMKorespondensi

ABSTRACT
Background: Superior vena cava syndrome (SVCS) is a collection of symptoms of superior vena cava due to
suppression by the masses in the superior mediastinum and is a medical emergency that needs to be managed immediately. Assessment profiles and survival rate is important in determining the treatment of SVCS patients.
Objective: To obtain the profile and survival rate of SVCS patients in Mangunkusomo Cipto Hospital and Dharmais Cancer Hospital.
Methods: This is a cohort restrospective design that was conducted on SVCS patients during January 2000 to
December 2011 at Cipto Mangunkusomo Hospital and Dharmais Cancer Hospital.
Results: The study population was composed of 151 study subjects. Most of them were male sex (76.2%), 18-60 years old (76.8%), and the economic status was private financing (51.7%). Type of primary tumor was lung tumor (52.3%).
The most frequent signs and symptoms found were dyspnea (84,1%), cough (68,2%) and face or neck swelling (12%). Many study subjects presented with a moderate SVCS grade (60.3%). Based on survival rate-analysis, there were several factors that showed significant differences in survival rate, the economic status (p=0.021), SVCS grade (p=0.006), pneumonia (p=0.013), and type of primary tumor (p=0.03)
Conclusions: The most SVCS patients are males, age range 18-60 years old, lung tumor, having dyspnea and
a moderate SVCS grade. Economic status, SVCS grade, pneumonia, and the type of primary tumor, play a role in survival rate of SVCS patients. Such factors should be considered in decision making for treatment of SVCS patients.
Key words: Superior vena cava syndrome, survival