Background: Metabolic syndrome is a combination of central obesity, elevated blood pressure, impaired glucose metabolism, and dyslipidemia. Its prevalence is increasing worldwide. Several previous studies showed various differences of lung functions in patients with and without metabolic syndrome .
Objective: To determine whether patients with metabolic syndrome had lower FEV1 percent predicted and FVC percent predicted than normal population.
Methods: The study design was cross-sectional study. Patients were grouped into subjects with and without metabolic syndrome who met the inclusion and exclusion criteria.
Results: There were 96 subjects of the study with a mean age of 42.74 ± 9.14. Metabolic syndrome group consisted of 48 subjects and there were 48 healthy subjects in control group. FVC percent predicted values in subjects with and without metabolic syndrome were 99.27 ± 20.35 vs. 116.22 ± 20.67 (p < 0.001), and FEV1 values were 116.05 ± 23.77 vs 130.06 ± 20.78 (p = 0.03). In patients with metabolic syndrome, 16.7% had FEV1 < 80% predicted that indicated decline in lung function (obstruction type), and 22.67% had FVC < 80 % predicted indicating a decline in lung function (restriction type).
Conclusion: Patient with metabolic syndrome had lower FEV1 and FVC values than normal population.
Keywords: Metabolic syndrome, pulmonary functions