Mega C Diatri, M. Harun Iskandar
Divisi Pulmonologi Departemen Ilmu Penyakit Dalam FK Universitas Hasanuddin Makassar

ABSTRACT
Background: Community-Acquired Pneumonia (CAP) had caused high prevalence of morbidity and mortality worlwide. Management of CAP depends on the severity of the disease. CURB-65 and PSI are the most frequently used clinical scoring system with high sensitivity and specifity in predicting mortality among inpatients with CAP. Procalcitonin (PCT) is a good biomarker for diagnosing CAP. High level of PCT indicates higher risk of complication among CAP patients, even if they were classified as low-risk by CURB-65 and PSI.
Objective: To determine the correlation between severity of CAP and PCT level.
Methods: Descriptive-analytic method was used in this cross-sectional study among CAP subjects in Dr. Wahidin Sudirohusodo Hospital, Makassar from September 2014 to January 2015. Severity of CAP was assessed with CURB-65 and PSI score. Initial PCT level was measured quantitatively with immunoluminometric method. Results: There are a total of 40 subjectsincluden in this study (mean age of 52 years). Range of CURB-65 score is 0-4, range of PSI socre 41-191, and range of PCT level 0,05-86,66. PCT showed significant correlation with both CURB-65 and PSI. PCT level (y) could be predicted using CURB-65(x): 1,33 + 5,22x. Mean PCT level had a significant difference among CURB-65 risk category, but it was not observed among PSI risk class. Age had a significant influence on mean PSI score. Comorbidty had no significant impact on CURB-65, so does the effect of the number of comorbidity on PSI score.
Conclusion: This study showed that severity assessment of CAP using CURB-65 score has been proved to be significantly correlated with PCT level. However, no significant correlation was observed with PSI score. Key words: Severity assessment of CAP, CURB-65 score, PSI score , PCT level.