Kartika Anastasia Kosasih1, Zulkifli Amin2, Astrid Priscilla Amanda3
1Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia
2Division of Respirology and Critical Illness, Department of Internal Medicine Universitas Indonesia, Jakarta, Indonesia 3Assistant Researcher, Division of Respirology and Critical Illness, Department of Internal Medicine Universitas Indonesia, Jakarta, Indonesia
ABSTRACT
Introduction: Tuberculosis (TB) is a leading cause of death worldwide alongside with HIV. Globally, there were an estimated 9.6 million new TB cases and 1.5 million deaths from TB in 2014. Tuberculosis-destroyed lung is a complication of severe pulmonary tuberculosis that can causes various respiratory symptoms and pulmonary dysfunction. Destroyed lung can seriously compromises long-term survival, so it is imperative to do the surgery. Objective: to determine the chance of survival in patients with tuberculosis-destroyed lung who underwent pulmonary resection.
Method: Literature searching on PubMed, Cochrane Library, ProQuest, EBSCOHost, Science Direct and ClinicalKey was conducted on March 15th, 2016. Three articles were included to be appraised for its validity and relevance using several aspect based on Center of Evidence-Based Medicine, University of Oxford for prognostic study. Result: Study by Byun CS. et al showed operative mortality of 6.8%, SE 2.9%, 95% CI (3.9% to 9.7%). The post- operative mortality rate in 5 years is 11.1%, SE 3.7%, 95% CI (7.4% to 14.8%) and 23.8%, SE 5%, 95% CI (18.8% to
28.8%) in 10 years. Rifaat A. et al revealed post-operative mortality rate of 7.1%, SE 6.8%, 95% CI (0% to 20.3%). Bai
L. et al presented post-operative mortality rate of 5.8%, SE 1.8%, 95% CI (4% to 7.6%).
Conclusion: Pulmonary resection for tuberculosis-destroyed lung patients can be achieved with low overall mortality rate (operative and post-operative).
Keywords: destroyed lung, mortality, resection, surgery, tuberculosis